Abstract

Naveed Ullah*, Mir Azam Khan, Afzal Haq Asif, Habib Ahmad, Taimur Khan, Taous Khan and Waqar Ahmad

The ethanolic extracts derived from cigarettes (Morven gold and Tander virginia) were screened for chemicals, spasmogenic and spasmolytic activities. M. gold extract showed a strong relaxant activity that is 70% against KCl induced contractions while T. virginia was found to have a mild spasmolytic activity of (06%). Furthermore, a moderate spasmogenic effect of M. gold had being measured, while no measurable spasmogenic activity has been shown by the T. virginia. It can be concluded from the current study that Morven gold has a strong spamsmogenic and spasmolytic activity, while the Tander is not found to be so efficient in either case. The chemicals found in sufficient quantity in both the extracts were tannins, saponin and glycosides. Minute quantity of carbohydrates were also been noted in M. gold . The presence of alkaloids were also been noted in excess quantity in T. virginia and less amount in M. gold. Further studies are necessary to elucidate its exact mechanism of action.