Abstract

Jeyaraj CP, Naresh MN, Malik NA, Sahoo BNK and Dutta BV

Plasma cell granuloma is a non-neoplastic lesion rather uncommonly seen in the maxillofacial region. Its etiology, biological behavior, ideal treatment and prognosis are still unclear and rather controversial. A rare case of this lesion affecting the gingiva is presented here, which could easily have been mistaken for a pyogenic granuloma, a peripheral giant sell reparative granuloma or a fibrous gingival epulis, had it not been for a detailed histological and Immunohistochemical study conducted on this lesion. Histopathological examination of the excised specimen revealed a proliferation of inflammatory cells, among which there was a typical predominance of plasma cells with the typical cartwheel shaped nuclei, set in a fibrovascular connective tissue stroma. Immunohistochemistry was employed for confirmatory diagnosis, and characteristically demonstrated the lambda and kappa light chains as seen in the polyclonal plasma cell population.