A study of aqueous and ethanolic extracts of Ocimum gratissimum and xylopia aethiopica and their antimicrobial activities

Abstract


Ijeh I.I., Omodamiro, O.D and Nwanna, I.J

Aqueous and ethanolic extracts of Ocimum gratissimum and xylopia aethiopica were analyzed for their antimicrobial activities against five pathogenic organisms; Staphylococcus aureus, Escherichia coli, Streptococcus fecalis, Pseudomonas aeruginosa and Lactobacilli. Ethanolic extracts of O. gratissimum had a minimum inhibitory concentration (MIC) of 30 g/ml against S. aureus, E. coli, P. aeruginosa and lactobacilli while for S. fecalis the MIC was 15 g/ml. Aqueous extracts of O. gratissimum had an MIC of 12.5 g/ml against S. aureus, E. coli and S. fecalis, while for P. aeruginosa and lactobacilli the MIC was 6.25 and 25 g/ml, respectively. Ethanolic extracts of X. aethiopica showed an MIC of 10 g/ml in the five organisms tested. While its aqueous extract gave an MIC of 30 g/ml for S. aureus and Lactobacilli, and 15 g/ml for E. coli, P. aeruginosa and S. fecalis. Our findings suggest that the anti-microbial activity of these spices reside in their aqueous fractions and also indicate that very low concentrations are required to achieve antimicrobial effects.

Share this article

Awards Nomination

Select your language of interest to view the total content in your interested language

Indexed In
  • Index Copernicus
  • Sherpa Romeo
  • Open J Gate
  • Academic Keys
  • ResearchBible
  • Airiti
  • CiteFactor
  • Electronic Journals Library
  • OCLC- WorldCat
  • Euro Pub
  • Leipzig University Library
  • German cancer Research Center