A systematic review of epidemiological studies on the association between smokeless tobacco use and coronary heart disease

Abstract


Muhammad Aziz Rahman1 *, Mohammad Afzal Mahmood1 , Nicola Spurrier1 , Mahmudur Rahman2 and Stephen Leeder3

A systematic review was conducted of epidemiological studies focusing on the association between smokeless tobacco (SLT) use and coronary heart disease (CHD) in order to summarize the evidence and to identify scope for further study in South Asian countries. PubMed and ISI Web of Science databases were searched to find epidemiological studies (cohort, case-control and cross-sectional) published until 27 October, 2011. The search revealed 592 relevant references, from which 18 epidemiological studies were selected. Among the 18 studies, 11 studies were conducted in Sweden, 4 in the USA, 1 in India, 1 in Bangladesh, and 1 study was multi-centric involving 52 countries. Twelve studies included only men and six studies included both sexes. Three studies used South Asian SLT products. Nine studies found no statistically significant positive association between SLT use and CHD, while nine studies did find a positive association. Results of these studies differed according to age, gender, and SLT constituents. Currently published research does not provide conclusive evidence regarding the association between SLT use and CHD. SLT products and usage pattern in South Asia differ from those in Western settings, and cannot be extrapolated immediately to South Asian settings.

Share this article

Awards Nomination

Select your language of interest to view the total content in your interested language

Indexed In
  • Index Copernicus
  • Google Scholar
  • Academic Keys
  • CiteFactor
  • Cosmos IF
  • Electronic Journals Library
  • Directory of Abstract Indexing for Journals
  • OCLC- WorldCat
  • Scientific Journal Impact Factor (SJIF)
  • ZB MED
  • Eurasian Scientific Journal Index
  • German cancer Research Center
  • International Institute of Organized Research
  • University of Vechta Library
  • Prerna Society of Technical Education and Research
  • Database for Statistics on Higher Education (DBH)
  • The Hamburg State University Library
  • University Library of Humboldt-Universität zu Berlin, Germany