Abstract

Anwar Khalid, Amir Waseem, Malik Saadullah, Uzair-Ur -Rehman, Sonia Khiljee, Ayesha Sethi, Muhammad Hassham Hassan Bin Asad, Fatima Rasool, Muhammad Khurram Waqas and Ghulam Murtaza*

The methanolic, hot water and cold water extracts of Pistacia Integerrima (gall), Polygonum Bistorta (root), Swetia Charita (stem) and Zingiber officinale (root) were screened against gram positive bacteria like Bacillus subtilis (ATCC 6633), Entereococcus faecalis ( ATCC 14506) and Staphylococcus aureus (ATCC 6538), and gram negative bacteria like Pseudomonas aeruginosa (ATCC 27853) and Salmonella typhi (ATCC 14028) for their antibacterial efficiency. Discs agar diffusion technique was used. The maximum zone of inhibition of 19 mm of methanolic extract of Zingiber officinale was observed against Staphylococcus aureus, while the maximum zone of inhibition of 15 mm of cold water extract of Zingiber officinale against Pseudomonas aeruginosa and 15 mm of cold water extract of Swetia Charita against Bacillus subtilis were observed. Standard drugs with antibiotic action like ceftriaxone, ceftriaxone sodium, cefuroxine, ciprofloxacin, gentamycine, levofloxacin, metronidazole and tranexamic acid were also used against these bacteria and compared their results with that of the plants extracts.