Abstract

KILANI A. M

The effects of methanolic extracts of the stem bark of Vitex doniana against some Entrobacteriaceae was investigated. Clinical isolates of Salmonella typhi, Shigella dysentariae and Escherichia coli were treated with extracts of the stem bark of V. doniana for antimicrobial activity using in vitro agar diffusion method and the minimum inhibitory concentration. The stem bark extracts were able to inhibit the growth pattern of the tested microorganisms. In all cases Shigella dysentariae showed the highest sensitivity. The results suggest that V. doniana may be valuable in the management of dysentery and gastroenteritis infections.