Abstract

P. Bansal *, R. Sannd, N. Srikanth and G. S. Lavekar

This study was conducted to establish the effect of a traditionally designed nutraceutical on stress related changes in selected immunoglobulin levels in the body. The nutraceutical was prepared from different potent herbs described in Ayurveda using standard operative procedures and were tested for heavy metal and microbial load. Initially, 21 subjects were selected in addition to 7 volunteers for control group who did not consume nutraceutical. Sampling was done at zero days and at fortnightly intervals. The levels of selected immunoglobulin IgG, IgA and IgM were estimated with turbidity metric immunoassay at different time intervals. The concentration of immunoglobulin IgA was 146±15.96 at zero day stage. The levels of these immunoglobulins were lower at all stages as compared to the concentration at zero day in trial group subjects whereas the concentration was significantly higher (t stat.>t critic. at pt critic. at pt critic. at pt critic. at p<0.05) anti-stress effect against stress related changes in immunoglobulin in the body due to the battery of stresses encountered at Antarctica.