Field evaluation of SD Bioline Malaria Antigen P.f® for Plasmodium falciparum malaria diagnosis in Nanoro, Burkina Faso

Abstract


*Halidou Tinto, Olivier Sombié, Innocent Valea, Ferdinand Lankoandé,SandrineYara , Palpouguini Lompo, Marc C Tahita, Adama Kazienga, Sayouba Ouédraogo,Hermann Sorgho, Maaike De Kroop, Raffaella Ravinetto

A study was conducted to assess the performance of the SD Bioline Malaria Antigen P.f® compared to the ‘’gold standard’’ microscopy as for the diagnosis of Plasmodium falciparum malaria in Nanoro, Burkina Faso. Microscopy and RDT diagnosis were performed on 254 blood samples. 78.09% (189/242) were positive by microscopy compared to 93.8% (227/242) diagnosed by RDT. The RDT test reported 39 false-positive results and one false-negative result. The RDT showed high sensitivity of 99.47% [IC95%: 98.56-100], with sensitivity increasing with increasing parasite density. RDT specificity was 26.42% [IC95%: 20.86-31.97]. Low specificity limits accuracy for malaria diagnosis. However, in areas of hyperendemic malaria, high sensitivity is preferable to over diagnosis.

Share this article

Awards Nomination

Select your language of interest to view the total content in your interested language

Indexed In
  • CAS Source Index (CASSI)
  • Index Copernicus
  • Sherpa Romeo
  • Open J Gate
  • Academic Keys
  • ResearchBible
  • Directory of Open Access Journals
  • CiteFactor
  • SCOPUS
  • Electronic Journals Library
  • OCLC- WorldCat
  • Publons
  • Euro Pub