Abstract

Gregory McIntireRecent laboratory studies have led to the identification of novel metabolites of antipsychotics in urine. These metabolites have further been demonstrated to enhance the sensitivity of LC/MSMS analysis of both forensic and toxicology samples. Knowledge of these metabolites may also be useful in functional mass spectrometry imaging. Finally, these metabolites are not limited to urine but are also resident in plasma.

Recent laboratory studies have led to the identification of novel metabolites of antipsychotics in urine. These metabolites have further been demonstrated to enhance the sensitivity of LC/MSMS analysis of both forensic and toxicology samples. Knowledge of these metabolites may also be useful in functional mass spectrometry imaging. Finally, these metabolites are not limited to urine but are also resident in plasma.