Abstract

Tamalli M., M.A.B. Gamal, Bioprabhu Sangar and Alghazal M.A.

Pharmaceutical products of widely differing forms are susceptible to microbial contamination (Aulton,2002). The presence of microorganisms in a pharmaceutical preparations may therefore, affects the consumer, the preparation either itself or both depending on the class of contaminants. The use of contaminated pharmaceutical preparations has proved hazardous to the health of the users.To determine the type and incidence of predominant microorganisms in certainnon-sterile pharmaceuticals immediately after collection.All pharmaceutical samples were subjected to the following examinations: total bacterial count and presence of microbial pathogens, using conventional techniques.Microbial load varied among the pharmaceutical preparations. Bacterial counts ranged from 10 to more than 103 CFU per ml org. Several measures, including equipment automation, monitoring programs and post-marketing surveillance are required to reduce the level of microbial contamination of non-sterile pharmaceutical products.