Molecular analysis of type III polyketide synthase (PKS) gene family from Zingiber officinale Rosc.

Abstract


Radhakrishnan E. K. and E. V. Soniya*

Enzymes of the type III polyketide synthase family is considered to have significant role in biosynthesis of structurally diverse polyketide scaffolds in Zingiber officinale. Genome wide analysis of polyketide synthase gene family in Z. officinale identified partial sequences of six members. Comparative sequence analysis showed that four of them ZoPKS2, 3, 4 and 6 were novel forms as revealed by the significant variations at the highly conserved regions. Phylogenetic analysis also showed separate clustering of the novel forms along with the non-chalcone forming PKSs. This sequence identified in the study forms the first and basic information of the PKS gene family from the Zingiberaceae

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