Abstract

Hossein Samadi Kafil *, Fatemeh Farahi Jahromi , Bahareh Hajikhani, Shahin Najar Pirayeh and Mohammad Aghazadeh

Helicobacter Pylori is a bacillus that naturally colonizes humans, living in gastric mucus. Association of H. pylori colonization of stomach with chronic gastritis, peptic ulcer and gastric malignancies has been well documented. In this study, we aimed to find presence of H. pylori in stool of HIV infected patients by PCR. 43 patients who had confirmed HIV-infection were subjected. Specific primers for hpaA (flagellar sheath adhesin) and ureB (urea amidohydrolase), of H. pylori were designed and, presence of the genome of H. pylori investigated by PCR method. 35 of the patients (81.39%) had CD4+ count below 200 and H. pylori was found in 30 patients (69.76%). Results show from screening by H. pylori in stool of HIV-infected patients that prevalence of this bacterium in these patients is high. This prevalence is similar to prevalence of H. pylori in HIV-non infected population.