Abstract

Nasrin Aghel*, Ali Zarei Mahmoudabadi and Loobat Darvishi

The aims of present study were to analysis of chemical compositions and evaluate anti-Candida activity of Dittrichia gravolence essential oil. The composition of the hydrodistilled essential oil from aerial parts of D. graveolens (L.) Greuter were grown in Iran investigated by gas chromatography-mass spectroscopy (GC/ MS). The major components, among the identified 22, were 1,8 Cineol (54.89%), PCymen (16.2%), [beta]-pinene (6.94%) and Borneol (5.44%) . Anti-Candida activity of the volatile oil of the aerial parts of D. gravolence against different isolates of Candida albicans was studied in vitro. AntiCandida activity was done using serial dilutions of volatile oil in Sabouraud’s dextrose agar (SDA). Agar well diffusion methods was used for detection minimum inhibitory concentration (MIC). MIC for 10 isolates of tested yeasts was 30.675 mg/ml.