Research Article
Predictors of surgical intervention for antenatally detected Ureteropelvic Junction Obstruction (UPJO): A prospective multivariate analysis
Author(s): Tarek Ahmed Mahmoud*, Esam El din Salem Morsy, Hany Abd Elraoof Ali Morsy, AbdelmoneimMohammed Abouzeid, Ahmed Mamdouh Abd Elhamed, Elnisr Rashed Mohamed and Hazem Mohamed Elmoghazy
Objective: We aimed to define the best timing for surgical intervention in infants born with antenatal hydronephrosis due to ureteropelvic junction obstruction to minimize the associated renal damage.
Material and methods: We prospectively followed infants born with antenatally diagnosed UPJO presented at our outpatient clinics for evidence of obstructive injury with a standard protocol with ultrasonography and renal scintigraphy. Indications for surgery included progression of hydronephrosis on serial ultrasonographic follow up, initial Differential Renal Function (DFR) ≤35% or >5% loss in subsequent studies, and recurrent Urinary Tract Infections (UTI). Univariate and multivariate analyses were utilized to define the predictors for surgical intervention, while the appropriate cut-off value of the initial APD was determined using the .. View More»
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