Kaya B

Department Internal Medicine Nephrology, Pathology and Biostatistics, Cukurova University, Adana, Turkey

Publications

• Research Article   
  The glomerular GCR expression, MEST score and clinical progression in patients with IgAN
  Author(s): Ala Tekin B*, Paydas S, Kaya B, Eren Erdogan K, Binokay H, Sertdemir Y, Balal M and Gonlusen G
  
  Aim: Glucocorticoids are used as the primary treatment in IgA Nephropathy (IgAN), and they manifest their effects by binding to intracellular glucocorticoid receptors. Studies have shown that Glucocorticoid Receptor Expression (GCR) expression correlates with steroid response in various diseases. Our aim was to evaluate the glomerular GCR expression, MEST score and clinical progression in patients with IgAN. Materials and methods: This study included 103 patients (58 male) with biopsy proven primary IgAN, who were treated with angiotensin converting enzyme inhibitor/angiotensin receptor blocker and methyl prednisolone and followed-up between 2002-2019. GCR expression determined immunohistochemically, MEST score, clinical and laboratory parameters of the patients were evaluated from the beginning of IgAN diagnosis. Results: .. View More»
  

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