N. Lakshmi Bhavani

Publications

• Research Article   
  A comparative study of in vivo antidiabetic activity, histopathology evaluation and gene expression studies in fruit and root crude methanolic extracts of Momordica charantia (L)., and Momordica dioica (Roxb)
  Author(s): M. Anjamma* and N. Lakshmi Bhavani
  
  Different parts of Momordica charantia and Momordica dioica are well known for their medicinal value. The present study aimed to evaluate the antidiabetic activity of crude methanolic fruit and root extracts of M. charantia and M. dioica in Alloxan induced diabetic male wistar rats. After dissecting the animal's collected liver, pancreas, and kidney, similarly studied the hepatic Notch2 gene expression in control, diabetic, and treated rats. Correspondingly we observed the glucose levels of control, diabetic, treated rats and positive control glibenclamide Momordica dioica root showed low glucose levels compared with other tested samples. In the same way, we studied, the pancreas of the Momordica charantia treated after diabetes is showing two folds up regulated Notch2 gene expression than Momordica dioica root extract.. View More»
  

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